Endocrine Abstracts

Background: Toxic adenoma (TA) is a rare cause of hyperthyroidism in children, representing less than 3% of cases, more frequently affecting girls. The risk of malignancy in pediatric autonomous nodules is unknown. Despite current guidelines on the management of TA, published case series reveal discrepancies in medical practice.Case presentation: We report a case of TA in a 7-year old boy, incidentally detected as a palpable mass during examination for l...

Background: ACTH-dependent Cushing’s syndrome (CS) is mostly associated with corticotroph adenomas or, infrequently, ectopic ACTH secretion(EAS). Adrenals may show diffuse bilateral enlargement or even macronodules. Adrenal metastases may occur in various cancers. They are often bilateral, irregular, with attenuation values >20 Hounsfield units(HU) on unenhanced CT scan and elevated SUVmax on FDG-PET scan. They may cause adrenal insufficiency due to the destruction of...